MolNFT v1 · #428888 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SIK2 (Q8CFH6)
Q8CFH6: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SIK2 (Q8CFH6)”. 6 pockets (best druggability 0.77). MolNFT v1 #428888 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8CFH6
- Type
- protein
- Length
- 931 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9C5cB57d1eDa7581935cB65276f4b016326De568
- Molecule
- SERINE/THREONINE-protein kinase SIK2
- UniProt
- Q8CFH6
- Pockets
- 6 · best druggability 0.77
Structure
1 distinct chain · 23% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase SIK2 | protein | 931 | 23% helix, 6% strand | Q8CFH6 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1014 | 0.77 | 0.79 | 69 | empty |
| 2 | 757 | 0.69 | 0.76 | 62 | empty |
| 3 | 419 | 0.57 | 0.74 | 47 | empty |
| 4 | 176 | 0.50 | 0.77 | 18 | empty |
| 5 | 128 | 0.47 | 0.78 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8CFH6
- Elsewhere: UniProt Q8CFH6 · AlphaFold DB Q8CFH6
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