MolNFT v1 · #428402 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B (Q2I6J0)
Q2I6J0: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B (Q2I6J0)”. 8 pockets (best druggability 0.81). MolNFT v1 #428402 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q2I6J0
- Type
- protein
- Length
- 1,226 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB765e36a52DF056e3d74166883b608B9e6599Dd2
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B
- UniProt
- Q2I6J0
- Pockets
- 8 · best druggability 0.81
Structure
1 distinct chain · 22% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B | protein | 1226 | 22% helix, 21% strand | Q2I6J0 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1175 | 0.81 | 0.82 | 122 | empty |
| 2 | 379 | 0.58 | 0.75 | 44 | empty |
| 3 | 213 | 0.57 | 0.80 | 31 | empty |
| 4 | 159 | 0.49 | 0.78 | 32 | empty |
| 5 | 69 | 0.42 | 0.80 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2I6J0
- Elsewhere: UniProt Q2I6J0 · AlphaFold DB Q2I6J0
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