MolNFT v1 · #428266 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (Q9WVR3)
Q9WVR3: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (Q9WVR3)”. 16 pockets (best druggability 0.70). MolNFT v1 #428266 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9WVR3
- Type
- protein
- Length
- 1,257 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x20691be19842188099108aB87e48b57BA599A09F
- Molecule
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
- UniProt
- Q9WVR3
- Pockets
- 16 · best druggability 0.70
Structure
1 distinct chain · 20% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | protein | 1257 | 20% helix, 22% strand | Q9WVR3 |
Pockets
16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 425 | 0.70 | 0.81 | 48 | empty |
| 2 | 302 | 0.66 | 0.82 | 49 | empty |
| 3 | 305 | 0.59 | 0.77 | 31 | empty |
| 4 | 196 | 0.54 | 0.79 | 31 | empty |
| 5 | 140 | 0.49 | 0.78 | 28 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WVR3
- Elsewhere: UniProt Q9WVR3 · AlphaFold DB Q9WVR3
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