MolNFT v1 · #428257 · protein
AlphaFold monomer V2.0 prediction for sonic hedgehog protein (Q92000)
Q92000: “AlphaFold monomer V2.0 prediction for sonic hedgehog protein (Q92000)”. 5 pockets (best druggability 0.70). MolNFT v1 #428257 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q92000
- Type
- protein
- Length
- 444 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xE4e5409cB506845d70744D216Bfd0506C6207BD9
- Molecule
- Sonic hedgehog protein
- UniProt
- Q92000
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 25% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sonic hedgehog protein | protein | 444 | 25% helix, 28% strand | Q92000 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 307 | 0.70 | 0.84 | 38 | empty |
| 2 | 460 | 0.64 | 0.77 | 48 | empty |
| 3 | 202 | 0.51 | 0.77 | 26 | empty |
| 4 | 76 | 0.35 | 0.75 | 15 | empty |
| 5 | 67 | 0.34 | 0.76 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92000
- Elsewhere: UniProt Q92000 · AlphaFold DB Q92000
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