MolNFT v1 · #428078 · protein
AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 1 (Q9Y566)
Q9Y566: “AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 1 (Q9Y566)”. 5 pockets (best druggability 0.64). MolNFT v1 #428078 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y566
- Type
- protein
- Length
- 2,161 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- SH3 and multiple ankyrin repeat domains protein 1
- UniProt
- Q9Y566
- Pockets
- 5 · best druggability 0.64
Structure
1 distinct chain · 12% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH3 and multiple ankyrin repeat domains protein 1 | protein | 2161 | 12% helix, 5% strand | Q9Y566 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.64 | 0.75 | 49 | empty |
| 2 | 136 | 0.41 | 0.75 | 24 | empty |
| 3 | 91 | 0.35 | 0.75 | 18 | empty |
| 4 | 69 | 0.34 | 0.76 | 18 | empty |
| 5 | 79 | 0.33 | 0.74 | 17 | empty |
Compared structures
- 8S1R · Crystal structure of SHANK1 PDZ in complex with a SLiM internal ligand · an experimental structure of the same protein · chain A against CCC, TM-score 0.05
- 6YX0 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YX0 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YX2 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YX2 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 7A00 · Crystal structure of SHANK1 PDZ in complex with L6F mutant of the C- terminal hexapeptide… · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 7A00 · Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide… · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 6YX1 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YX1 · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YWZ · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 6YWZ · Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid · an experimental structure of the same protein · chain A against B, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y566
- Elsewhere: UniProt Q9Y566 · AlphaFold DB Q9Y566
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