MolNFT v1 · #427991 · protein
AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 5 (Q5R732)
Q5R732: “AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 5 (Q5R732)”. 5 pockets (best druggability 0.70). MolNFT v1 #427991 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5R732
- Type
- protein
- Length
- 423 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x26dEdD8528d07680013a2f005A1D1d358398e2E5
- Molecule
- SH2 domain-containing protein 5
- UniProt
- Q5R732
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 24% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH2 domain-containing protein 5 | protein | 423 | 24% helix, 20% strand | Q5R732 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 528 | 0.70 | 0.80 | 51 | empty |
| 2 | 437 | 0.62 | 0.76 | 44 | empty |
| 3 | 159 | 0.57 | 0.81 | 31 | empty |
| 4 | 189 | 0.48 | 0.76 | 30 | empty |
| 5 | 186 | 0.46 | 0.75 | 32 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5R732
- Elsewhere: UniProt Q5R732 · AlphaFold DB Q5R732
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