MolNFT v1 · #427966 · protein

AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 1B (O14796)

O14796: “AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 1B (O14796)”. 1 pocket (best druggability 0.44). MolNFT v1 #427966 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O14796
Type: protein
Length: 132 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
Molecule: SH2 domain-containing protein 1B
UniProt: O14796
Pockets: 1 · best druggability 0.44

Structure

1 distinct chain · 15% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SH2 domain-containing protein 1B	protein	132	15% helix, 23% strand	O14796

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.44	0.83	15	empty

Compared structures

5KAZ · Human SH2D1B structure · an experimental structure of the same protein · chain A against A, TM-score 0.75
5KAZ · Human SH2D1B structure · an experimental structure of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14796
Elsewhere: UniProt O14796 · AlphaFold DB O14796

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