MolNFT v1 · #427927 · protein
AlphaFold monomer V2.0 prediction for small G protein signaling modulator 2 (O43147)
O43147: “AlphaFold monomer V2.0 prediction for small G protein signaling modulator 2 (O43147)”. 8 pockets (best druggability 0.59). MolNFT v1 #427927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43147
- Type
- protein
- Length
- 1,006 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x64E3FBA566A8615E822A975222Ed2beFd3a0A755
- Molecule
- Small G protein signaling modulator 2
- UniProt
- O43147
- Pockets
- 8 · best druggability 0.59
Structure
1 distinct chain · 48% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Small G protein signaling modulator 2 | protein | 1006 | 48% helix, 7% strand | O43147 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 447 | 0.59 | 0.75 | 48 | empty |
| 2 | 199 | 0.54 | 0.78 | 33 | empty |
| 3 | 166 | 0.51 | 0.78 | 30 | empty |
| 4 | 146 | 0.44 | 0.76 | 21 | empty |
| 5 | 73 | 0.43 | 0.81 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43147
- Elsewhere: UniProt O43147 · AlphaFold DB O43147
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