MolNFT v1 · #427869 · protein

AlphaFold monomer V2.0 prediction for sphingosine-1-phosphate lyase (Q05567)

Q05567: “AlphaFold monomer V2.0 prediction for sphingosine-1-phosphate lyase (Q05567)”. 10 pockets (best druggability 0.54). MolNFT v1 #427869 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q05567
Type: protein
Length: 589 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7AdE9AB197a9650d2B3aE28c73Eee20DfF832801
Molecule: Sphingosine-1-phosphate lyase
UniProt: Q05567
Pockets: 10 · best druggability 0.54

Structure

1 distinct chain · 51% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sphingosine-1-phosphate lyase	protein	589	51% helix, 11% strand	Q05567

Pockets

10 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	321	0.54	0.74	37	empty
2	274	0.49	0.73	37	empty
3	99	0.47	0.80	27	empty
4	116	0.45	0.78	17	empty
5	108	0.41	0.77	22	empty

Compared structures

3MC6 · Crystal structure of ScDPL1 · an experimental structure of the same protein · chain A against A, TM-score 0.72
3MC6 · Crystal structure of SCDPL1 · an experimental structure of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05567
Elsewhere: UniProt Q05567 · AlphaFold DB Q05567

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