MolNFT v1 · #427800 · protein
AlphaFold monomer V2.0 prediction for SODIUM/GLUCOSE cotransporter (P96169)
P96169: “AlphaFold monomer V2.0 prediction for SODIUM/GLUCOSE cotransporter (P96169)”. 6 pockets (best druggability 0.83). MolNFT v1 #427800 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P96169
- Type
- protein
- Length
- 543 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- SODIUM/GLUCOSE cotransporter
- UniProt
- P96169
- Pockets
- 6 · best druggability 0.83
Structure
1 distinct chain · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/GLUCOSE cotransporter | protein | 543 | 76% helix, 0% strand | P96169 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 942 | 0.83 | 0.84 | 81 | empty |
| 2 | 300 | 0.64 | 0.80 | 40 | empty |
| 3 | 101 | 0.45 | 0.79 | 18 | empty |
| 4 | 121 | 0.43 | 0.75 | 15 | empty |
| 5 | 62 | 0.35 | 0.76 | 12 | empty |
Compared structures
- 3DH4 · Crystal Structure of Sodium/Sugar symporter with bound Galactose from vibrio… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 3DH4 · Crystal structure of SODIUM/SUGAR symporter with bound galactose from vibrio… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2XQ2 · Structure of the K294A mutant of vsglt · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 2XQ2 · Structure of the K294A mutant of vSGLT · an experimental structure of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96169
- Elsewhere: UniProt P96169 · AlphaFold DB P96169
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