MolNFT v1 · #427171 · protein

AlphaFold monomer V2.0 prediction for phosphatidylinositol transfer protein SFH5 (A6ZQI5)

A6ZQI5: “AlphaFold monomer V2.0 prediction for phosphatidylinositol transfer protein SFH5 (A6ZQI5)”. 5 pockets (best druggability 0.77). MolNFT v1 #427171 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A6ZQI5
Type: protein
Length: 294 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
Molecule: Phosphatidylinositol transfer protein SFH5
UniProt: A6ZQI5
Pockets: 5 · best druggability 0.77

Structure

1 distinct chain · 53% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphatidylinositol transfer protein SFH5	protein	294	53% helix, 12% strand	A6ZQI5

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	330	0.77	0.88	42	empty
2	84	0.50	0.83	17	empty
3	60	0.38	0.79	15	empty
4	105	0.38	0.75	20	empty
5	71	0.31	0.74	15	empty

Compared structures

6W32 · Crystal structure of SFH5 · an experimental structure of the same protein · chain A against B, TM-score 0.95
6W32 · Crystal structure of Sfh5 · an experimental structure of the same protein · chain A against B, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A6ZQI5
Elsewhere: UniProt A6ZQI5 · AlphaFold DB A6ZQI5

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