MolNFT v1 · #427144 · protein

AlphaFold monomer V2.0 prediction for PHOSPHATIDYLINOSITOL/PHOSPHATIDYLCHOLINE transfer protein SFH5 (Q8GXC6)

Q8GXC6: “AlphaFold monomer V2.0 prediction for PHOSPHATIDYLINOSITOL/PHOSPHATIDYLCHOLINE transfer protein SFH5 (Q8GXC6)”. 4 pockets (best druggability 0.83). MolNFT v1 #427144 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8GXC6
Type: protein
Length: 612 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xFFa42DE6Aaf8B5B434aaffB26fCaEC53a3cDB97a
Molecule: PHOSPHATIDYLINOSITOL/PHOSPHATIDYLCHOLINE transfer protein SFH5
UniProt: Q8GXC6
Pockets: 4 · best druggability 0.83

Structure

1 distinct chain · 46% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PHOSPHATIDYLINOSITOL/PHOSPHATIDYLCHOLINE transfer protein SFH5	protein	612	46% helix, 5% strand	Q8GXC6

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	863	0.83	0.84	79	empty
2	305	0.66	0.81	37	empty
3	137	0.41	0.75	22	empty
4	92	0.36	0.75	16	empty

Compared structures

7Y10 · Crystal structure of AtSFH5-Sec14 in complex with DPPA · an experimental structure of the same protein · chain A against A, TM-score 0.46
7Y11 · Crystal structure of AtSFH5-Sec14 in complex with egg PA · an experimental structure of the same protein · chain A against A, TM-score 0.46

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8GXC6
Elsewhere: UniProt Q8GXC6 · AlphaFold DB Q8GXC6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.