MolNFT v1 · #426874 · protein
AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SETDB2 (Q06ZW3)
Q06ZW3: “AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SETDB2 (Q06ZW3)”. 4 pockets (best druggability 0.74). MolNFT v1 #426874 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q06ZW3
- Type
- protein
- Length
- 551 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- Histone-lysine N-methyltransferase SETDB2
- UniProt
- Q06ZW3
- Pockets
- 4 · best druggability 0.74
Structure
1 distinct chain · 18% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone-lysine N-methyltransferase SETDB2 | protein | 551 | 18% helix, 14% strand | Q06ZW3 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 884 | 0.74 | 0.78 | 82 | empty |
| 2 | 54 | 0.69 | 0.97 | 20 | empty |
| 3 | 763 | 0.69 | 0.76 | 62 | empty |
| 4 | 62 | 0.32 | 0.76 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06ZW3
- Elsewhere: UniProt Q06ZW3 · AlphaFold DB Q06ZW3
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