MolNFT v1 · #426854 · protein
AlphaFold monomer V2.0 prediction for set domain-containing protein 8 (O14135)
O14135: “AlphaFold monomer V2.0 prediction for set domain-containing protein 8 (O14135)”. 6 pockets (best druggability 0.68). MolNFT v1 #426854 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O14135
- Type
- protein
- Length
- 429 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80DFF74473FD79110bd730F367842ad5E57E8738
- Molecule
- Set domain-containing protein 8
- UniProt
- O14135
- Pockets
- 6 · best druggability 0.68
Structure
1 distinct chain · 47% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Set domain-containing protein 8 | protein | 429 | 47% helix, 17% strand | O14135 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 369 | 0.68 | 0.81 | 52 | empty |
| 2 | 228 | 0.53 | 0.77 | 34 | empty |
| 3 | 61 | 0.38 | 0.79 | 16 | empty |
| 4 | 90 | 0.36 | 0.75 | 21 | empty |
| 5 | 63 | 0.33 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14135
- Elsewhere: UniProt O14135 · AlphaFold DB O14135
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