MolNFT v1 · #426827 · protein
AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase, H3 lysine-36 specific (O14026)
O14026: “AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase, H3 lysine-36 specific (O14026)”. 6 pockets (best druggability 0.80). MolNFT v1 #426827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O14026
- Type
- protein
- Length
- 798 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
- UniProt
- O14026
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 34% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone-lysine N-methyltransferase, H3 lysine-36 specific | protein | 798 | 34% helix, 9% strand | O14026 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 700 | 0.80 | 0.84 | 70 | empty |
| 2 | 259 | 0.64 | 0.82 | 26 | empty |
| 3 | 345 | 0.57 | 0.76 | 43 | empty |
| 4 | 131 | 0.56 | 0.83 | 29 | empty |
| 5 | 64 | 0.43 | 0.81 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14026
- Elsewhere: UniProt O14026 · AlphaFold DB O14026
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.