GL1X · GenesisL1 explorer

MolNFT v1 · #426820 · protein

AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase, H3 lysine-36 specific (P0CO29)

P0CO29: “AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase, H3 lysine-36 specific (P0CO29)”. 8 pockets (best druggability 0.83). MolNFT v1 #426820 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P0CO29
Type
protein
Length
834 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBDaba9F1bAE78Bc8b4574B9BB809390289445980
Molecule
Histone-lysine N-methyltransferase, H3 lysine-36 specific
UniProt
P0CO29
Pockets
8 · best druggability 0.83

Structure

1 distinct chain · 34% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHistone-lysine N-methyltransferase, H3 lysine-36 specificprotein83434% helix, 9% strandP0CO29

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17540.830.8681empty
2750.700.9518empty
32940.680.8340empty
42550.570.7824empty
52820.540.7635empty

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