MolNFT v1 · #426760 · protein
AlphaFold monomer V2.0 prediction for sestrin-1 (P58006)
P58006: “AlphaFold monomer V2.0 prediction for sestrin-1 (P58006)”. 10 pockets (best druggability 0.66). MolNFT v1 #426760 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P58006
- Type
- protein
- Length
- 492 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA7381fE9bA15c95992d24BC2A3Bb44aB0Cd83e3f
- Molecule
- Sestrin-1
- UniProt
- P58006
- Pockets
- 10 · best druggability 0.66
Structure
1 distinct chain · 57% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sestrin-1 | protein | 492 | 57% helix, 3% strand | P58006 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.66 | 0.92 | 21 | empty |
| 2 | 109 | 0.64 | 0.88 | 24 | empty |
| 3 | 239 | 0.54 | 0.77 | 31 | empty |
| 4 | 245 | 0.48 | 0.73 | 32 | empty |
| 5 | 74 | 0.41 | 0.80 | 19 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58006
- Elsewhere: UniProt P58006 · AlphaFold DB P58006
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