MolNFT v1 · #425827 · protein
AlphaFold monomer V2.0 prediction for semaphorin-3E (P70275)
P70275: “AlphaFold monomer V2.0 prediction for semaphorin-3E (P70275)”. 7 pockets (best druggability 0.74). MolNFT v1 #425827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P70275
- Type
- protein
- Length
- 775 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- Semaphorin-3E
- UniProt
- P70275
- Pockets
- 7 · best druggability 0.74
Structure
1 distinct chain · 16% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Semaphorin-3E | protein | 775 | 16% helix, 34% strand | P70275 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 827 | 0.74 | 0.78 | 54 | empty |
| 2 | 196 | 0.55 | 0.79 | 32 | empty |
| 3 | 337 | 0.55 | 0.75 | 33 | empty |
| 4 | 176 | 0.50 | 0.77 | 17 | empty |
| 5 | 97 | 0.40 | 0.76 | 23 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P70275
- Elsewhere: UniProt P70275 · AlphaFold DB P70275
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