MolNFT v1 · #425102 · protein
AlphaFold monomer V2.0 prediction for protein translocase subunit secy (Q60175)
Q60175: “AlphaFold monomer V2.0 prediction for protein translocase subunit secy (Q60175)”. 5 pockets (best druggability 0.78). MolNFT v1 #425102 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q60175
- Type
- protein
- Length
- 436 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x91173477EE1A4BaD13DF68ee48b56c467d07e9fe
- Molecule
- Protein translocase subunit secy
- UniProt
- Q60175
- Pockets
- 5 · best druggability 0.78
Structure
1 distinct chain · 66% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein translocase subunit secy | protein | 436 | 66% helix, 5% strand | Q60175 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 972 | 0.78 | 0.80 | 96 | empty |
| 2 | 437 | 0.67 | 0.79 | 55 | empty |
| 3 | 72 | 0.33 | 0.74 | 16 | empty |
| 4 | 60 | 0.32 | 0.75 | 15 | empty |
| 5 | 70 | 0.29 | 0.73 | 16 | empty |
Compared structures
- 1RHZ · The structure of a protein conducting channel · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1RHZ · The structure of a protein conducting channel · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 2YXQ · The plug domain of the secy protein stablizes the closed state of the translocation… · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 2YXQ · The plug domain of the SecY protein stablizes the closed state of the translocation… · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 2YXR · The plug domain of the secy protein stablizes the closed state of the translocation… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 2YXR · The plug domain of the SecY protein stablizes the closed state of the translocation… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1RH5 · The structure of a protein conducting channel · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1RH5 · The structure of a protein conducting channel · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 4V4N · Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex · an experimental structure of the same protein · chain A against AX, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60175
- Elsewhere: UniProt Q60175 · AlphaFold DB Q60175
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