MolNFT v1 · #423499 · protein
AlphaFold monomer V2.0 prediction for exocyst complex component SEC8 (O74562)
O74562: “AlphaFold monomer V2.0 prediction for exocyst complex component SEC8 (O74562)”. 18 pockets (best druggability 0.72). MolNFT v1 #423499 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O74562
- Type
- protein
- Length
- 1,073 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Exocyst complex component SEC8
- UniProt
- O74562
- Pockets
- 18 · best druggability 0.72
Structure
1 distinct chain · 65% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Exocyst complex component SEC8 | protein | 1073 | 65% helix, 1% strand | O74562 |
Pockets
18 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 718 | 0.72 | 0.78 | 72 | empty |
| 2 | 120 | 0.70 | 0.91 | 26 | empty |
| 3 | 218 | 0.66 | 0.84 | 30 | empty |
| 4 | 275 | 0.61 | 0.79 | 39 | empty |
| 5 | 66 | 0.60 | 0.90 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74562
- Elsewhere: UniProt O74562 · AlphaFold DB O74562
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