MolNFT v1 · #423492 · protein
AlphaFold monomer V2.0 prediction for arf guanine nucleotide exchange factor SEC74 (Q10491)
Q10491: “AlphaFold monomer V2.0 prediction for arf guanine nucleotide exchange factor SEC74 (Q10491)”. 9 pockets (best druggability 0.70). MolNFT v1 #423492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q10491
- Type
- protein
- Length
- 928 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- Arf guanine nucleotide exchange factor SEC74
- UniProt
- Q10491
- Pockets
- 9 · best druggability 0.70
Structure
1 distinct chain · 33% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Arf guanine nucleotide exchange factor SEC74 | protein | 928 | 33% helix, 7% strand | Q10491 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 824 | 0.70 | 0.76 | 68 | empty |
| 2 | 365 | 0.68 | 0.81 | 39 | empty |
| 3 | 578 | 0.64 | 0.75 | 49 | empty |
| 4 | 335 | 0.60 | 0.77 | 23 | empty |
| 5 | 66 | 0.59 | 0.89 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q10491
- Elsewhere: UniProt Q10491 · AlphaFold DB Q10491
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