MolNFT v1 · #423150 · protein
AlphaFold monomer V2.0 prediction for suppressor of disruption of tfiis (P53078)
P53078: “AlphaFold monomer V2.0 prediction for suppressor of disruption of tfiis (P53078)”. 5 pockets (best druggability 0.81). MolNFT v1 #423150 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P53078
- Type
- protein
- Length
- 280 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Suppressor of disruption of tfiis
- UniProt
- P53078
- Pockets
- 5 · best druggability 0.81
Structure
1 distinct chain · 49% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Suppressor of disruption of tfiis | protein | 280 | 49% helix, 9% strand | P53078 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.81 | 0.97 | 29 | empty |
| 2 | 98 | 0.42 | 0.78 | 17 | empty |
| 3 | 51 | 0.35 | 0.79 | 18 | empty |
| 4 | 92 | 0.34 | 0.74 | 14 | empty |
| 5 | 70 | 0.31 | 0.74 | 12 | empty |
Compared structures
- 3ONN · Crystal structure of 5'-nucleotidase SDT1 from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.88
- 3ONN · Crystal structure of 5'-nucleotidase SDT1 from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.88
- 3NUQ · Structure of a putative nucleotide phosphatase from Saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.88
- 3NUQ · Structure of a putative nucleotide phosphatase from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.88
- 3OPX · Crystal structure of pyrimidine 5 -nucleotidase SDT1 from saccharomyces cerevisiae… · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 3OPX · Crystal structure of pyrimidine 5 -nucleotidase SDT1 from Saccharomyces cerevisiae… · an experimental structure of the same protein · chain A against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53078
- Elsewhere: UniProt P53078 · AlphaFold DB P53078
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