MolNFT v1 · #422685 · protein
AlphaFold monomer V2.0 prediction for succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (P31040)
P31040: “AlphaFold monomer V2.0 prediction for succinate dehydrogenase [ubiquinone] flavoprotein subunit…”. 6 pockets (best druggability 0.79). MolNFT v1 #422685 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31040
- Type
- protein
- Length
- 664 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x14905748151782814d1AA807Ec0342Dd8879634b
- Molecule
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- UniProt
- P31040
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 33% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | protein | 664 | 33% helix, 22% strand | P31040 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 393 | 0.79 | 0.88 | 66 | empty |
| 2 | 256 | 0.55 | 0.77 | 35 | empty |
| 3 | 252 | 0.51 | 0.75 | 31 | empty |
| 4 | 179 | 0.46 | 0.75 | 26 | empty |
| 5 | 78 | 0.39 | 0.78 | 15 | empty |
Compared structures
- 8GS8 · cryo-EM structure of the human respiratory complex II · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 6VAX · Crystal structure of human sdha-ADHAF2 assembly intermediate · an experimental structure of the same protein · chain A against A, TM-score 0.86
- 6VAX · Crystal structure of human SDHA-SDHAF2 assembly intermediate · an experimental structure of the same protein · chain A against A, TM-score 0.86
- 8DYE · Crystal structure of human SDHA-SDHAF4 assembly intermediate · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 8DYD · Crystal structure of human SDHA-SDHAF2-SDHAF4 assembly intermediate · an experimental structure of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31040
- Elsewhere: UniProt P31040 · AlphaFold DB P31040
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