MolNFT v1 · #422547 · protein
AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25 (A7A0P0)
A7A0P0: “AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25 (A7A0P0)”. 20 pockets (best druggability 0.76). MolNFT v1 #422547 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7A0P0
- Type
- protein
- Length
- 1,252 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x01970A7586aE074a277adA45533563056BA700c1
- Molecule
- Guanine nucleotide exchange factor SDC25
- UniProt
- A7A0P0
- Pockets
- 20 · best druggability 0.76
Structure
1 distinct chain · 47% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor SDC25 | protein | 1252 | 47% helix, 6% strand | A7A0P0 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 734 | 0.76 | 0.81 | 103 | empty |
| 2 | 585 | 0.70 | 0.79 | 63 | empty |
| 3 | 297 | 0.69 | 0.83 | 39 | empty |
| 4 | 127 | 0.68 | 0.90 | 22 | empty |
| 5 | 176 | 0.62 | 0.83 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7A0P0
- Elsewhere: UniProt A7A0P0 · AlphaFold DB A7A0P0
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