GL1X · GenesisL1 explorer

MolNFT v1 · #422527 · protein

AlphaFold monomer V2.0 prediction for protein SDA1 (P53313)

P53313: “AlphaFold monomer V2.0 prediction for protein SDA1 (P53313)”. 6 pockets (best druggability 0.67). MolNFT v1 #422527 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P53313
Type
protein
Length
767 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
Protein SDA1
UniProt
P53313
Pockets
6 · best druggability 0.67

Structure

1 distinct chain · 61% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein SDA1protein76761% helix, 0% strandP53313

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18530.670.7482empty
25730.650.7652empty
31900.500.7626empty
42140.450.7332empty
51120.410.7623empty

Compared structures

  • 6YLG · Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement) · an experimental structure of the same protein · chain A against t, TM-score 0.51
  • 6YLH · Rix1-Rea1 pre-60S particle - full composite structure · an experimental structure of the same protein · chain A against t, TM-score 0.51
  • 5JCS · Cryo-EM structure of the RIX1-REA1 pre-60S particle · an experimental structure of the same protein · chain A against r, TM-score 0.25

Analyse

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