MolNFT v1 · #421626 · protein

AlphaFold monomer V2.0 prediction for protein SCO2 homolog, mitochondrial (O43819)

O43819: “AlphaFold monomer V2.0 prediction for protein SCO2 homolog, mitochondrial (O43819)”. 1 pocket (best druggability 0.47). MolNFT v1 #421626 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O43819
Type: protein
Length: 266 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xBCbF010796f43F87eb3a18895Cb522A7404eFA25
Molecule: Protein SCO2 homolog, mitochondrial
UniProt: O43819
Pockets: 1 · best druggability 0.47

Structure

1 distinct chain · 36% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein SCO2 homolog, mitochondrial	protein	266	36% helix, 15% strand	O43819

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	161	0.47	0.76	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2RLI · Solution structure of Cu(I) human Sco2 · an experimental structure of the same protein · chain A against A, TM-score 0.54
2RLI · Solution structure of CU(I) human SCO2 · an experimental structure of the same protein · chain A against A, TM-score 0.54

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43819
Elsewhere: UniProt O43819 · AlphaFold DB O43819

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