MolNFT v1 · #421595 · protein
AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit gamma (Q9WU39)
Q9WU39: “AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit gamma (Q9WU39)”. 9 pockets (best druggability 0.64). MolNFT v1 #421595 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9WU39
- Type
- protein
- Length
- 655 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- Amiloride-sensitive sodium channel subunit gamma
- UniProt
- Q9WU39
- Pockets
- 9 · best druggability 0.64
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amiloride-sensitive sodium channel subunit gamma | protein | 655 | 36% helix, 21% strand | Q9WU39 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 401 | 0.64 | 0.78 | 37 | empty |
| 2 | 265 | 0.56 | 0.77 | 29 | empty |
| 3 | 132 | 0.41 | 0.75 | 25 | empty |
| 4 | 74 | 0.39 | 0.78 | 20 | empty |
| 5 | 86 | 0.35 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WU39
- Elsewhere: UniProt Q9WU39 · AlphaFold DB Q9WU39
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