MolNFT v1 · #421590 · protein
AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit beta-2 (O13262)
O13262: “AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit beta-2 (O13262)”. 8 pockets (best druggability 0.63). MolNFT v1 #421590 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O13262
- Type
- protein
- Length
- 646 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- Amiloride-sensitive sodium channel subunit beta-2
- UniProt
- O13262
- Pockets
- 8 · best druggability 0.63
Structure
1 distinct chain · 40% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amiloride-sensitive sodium channel subunit beta-2 | protein | 646 | 40% helix, 20% strand | O13262 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 303 | 0.63 | 0.80 | 37 | empty |
| 2 | 173 | 0.61 | 0.83 | 25 | empty |
| 3 | 207 | 0.56 | 0.79 | 24 | empty |
| 4 | 237 | 0.54 | 0.77 | 26 | empty |
| 5 | 118 | 0.41 | 0.75 | 22 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O13262
- Elsewhere: UniProt O13262 · AlphaFold DB O13262
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