MolNFT v1 · #421574 · protein
AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit alpha (K7GET2)
K7GET2: “AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit alpha (K7GET2)”. 9 pockets (best druggability 0.64). MolNFT v1 #421574 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- K7GET2
- Type
- protein
- Length
- 642 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA98E98d7D7aC99F2d3D548BF567847cac90aca12
- Molecule
- Amiloride-sensitive sodium channel subunit alpha
- UniProt
- K7GET2
- Pockets
- 9 · best druggability 0.64
Structure
1 distinct chain · 33% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amiloride-sensitive sodium channel subunit alpha | protein | 642 | 33% helix, 19% strand | K7GET2 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 403 | 0.64 | 0.78 | 39 | empty |
| 2 | 250 | 0.56 | 0.77 | 26 | empty |
| 3 | 163 | 0.47 | 0.76 | 22 | empty |
| 4 | 93 | 0.40 | 0.75 | 14 | empty |
| 5 | 72 | 0.34 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt K7GET2
- Elsewhere: UniProt K7GET2 · AlphaFold DB K7GET2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.