MolNFT v1 · #421573 · protein
AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit alpha (H2Q5A1)
H2Q5A1: “AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit alpha (H2Q5A1)”. 8 pockets (best druggability 0.69). MolNFT v1 #421573 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- H2Q5A1
- Type
- protein
- Length
- 692 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c401a2AE9a06b2E7F7452570800CDb8584B970F
- Molecule
- Amiloride-sensitive sodium channel subunit alpha
- UniProt
- H2Q5A1
- Pockets
- 8 · best druggability 0.69
Structure
1 distinct chain · 28% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amiloride-sensitive sodium channel subunit alpha | protein | 692 | 28% helix, 17% strand | H2Q5A1 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.69 | 0.78 | 52 | empty |
| 2 | 187 | 0.47 | 0.75 | 26 | empty |
| 3 | 83 | 0.46 | 0.81 | 14 | empty |
| 4 | 130 | 0.40 | 0.75 | 16 | empty |
| 5 | 79 | 0.38 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H2Q5A1
- Elsewhere: UniProt H2Q5A1 · AlphaFold DB H2Q5A1
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