MolNFT v1 · #421524 · protein
AlphaFold monomer V2.0 prediction for sodium channel protein type 8 subunit alpha (O88420)
O88420: “AlphaFold monomer V2.0 prediction for sodium channel protein type 8 subunit alpha (O88420)”. 20 pockets (best druggability 0.87). MolNFT v1 #421524 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88420
- Type
- protein
- Length
- 1,978 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA8d7cbC2919d19a108331CA502e884dCD605E612
- Molecule
- Sodium channel protein type 8 subunit alpha
- UniProt
- O88420
- Pockets
- 20 · best druggability 0.87
Structure
1 distinct chain · 55% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium channel protein type 8 subunit alpha | protein | 1978 | 55% helix, 3% strand | O88420 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1167 | 0.87 | 0.87 | 101 | empty |
| 2 | 962 | 0.75 | 0.78 | 76 | empty |
| 3 | 891 | 0.75 | 0.79 | 82 | empty |
| 4 | 538 | 0.68 | 0.78 | 45 | empty |
| 5 | 267 | 0.64 | 0.81 | 38 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88420
- Elsewhere: UniProt O88420 · AlphaFold DB O88420
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