MolNFT v1 · #421484 · protein
AlphaFold monomer V2.0 prediction for sodium channel protein type 1 subunit alpha (P04774)
P04774: “AlphaFold monomer V2.0 prediction for sodium channel protein type 1 subunit alpha (P04774)”. 20 pockets (best druggability 0.85). MolNFT v1 #421484 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P04774
- Type
- protein
- Length
- 2,009 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x16C867aF28165664B3FC5A5E54F51be204a1Beb5
- Molecule
- Sodium channel protein type 1 subunit alpha
- UniProt
- P04774
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 54% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium channel protein type 1 subunit alpha | protein | 2009 | 54% helix, 4% strand | P04774 |
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1109 | 0.85 | 0.86 | 92 | empty |
| 2 | 889 | 0.76 | 0.79 | 94 | empty |
| 3 | 946 | 0.75 | 0.78 | 83 | empty |
| 4 | 446 | 0.68 | 0.80 | 46 | empty |
| 5 | 54 | 0.66 | 0.95 | 16 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04774
- Elsewhere: UniProt P04774 · AlphaFold DB P04774
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