MolNFT v1 · #421177 · protein
AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein cleavage-activating protein (Q5MNU5)
Q5MNU5 · Sterol regulatory element-binding protein cleavage…: “AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein cleavage-activating protein…”. 15 pockets (best druggability 0.77). MolNFT v1 #421177 on…
- Accession
- Q5MNU5
- Type
- protein
- Length
- 1,279 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x91cB1A9982C8247E3BC25D698cCCD89D78d736B6
- Molecule
- Sterol regulatory element-binding protein cleavage- activating protein
- UniProt
- Q5MNU5
- Pockets
- 15 · best druggability 0.77
Structure
1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol regulatory element-binding protein cleavage- activating protein | protein | 1279 | 28% helix, 20% strand | Q5MNU5 |
Pockets
15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 690 | 0.77 | 0.82 | 65 | empty |
| 2 | 705 | 0.71 | 0.77 | 64 | empty |
| 3 | 1154 | 0.69 | 0.74 | 78 | empty |
| 4 | 79 | 0.69 | 0.93 | 22 | empty |
| 5 | 68 | 0.56 | 0.88 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5MNU5
- Elsewhere: UniProt Q5MNU5 · AlphaFold DB Q5MNU5
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