MolNFT v1 · #421173 · protein
AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein cleavage-activating protein (A6QM06)
A6QM06 · Sterol regulatory element-binding protein cleavage…: “AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein cleavage-activating protein…”. 18 pockets (best druggability 0.75). MolNFT v1 #421173 on…
- Accession
- A6QM06
- Type
- protein
- Length
- 1,278 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb21ec8561536D7DEd13EC0Ed01b162cd7EB5dE01
- Molecule
- Sterol regulatory element-binding protein cleavage- activating protein
- UniProt
- A6QM06
- Pockets
- 18 · best druggability 0.75
Structure
1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol regulatory element-binding protein cleavage- activating protein | protein | 1278 | 28% helix, 20% strand | A6QM06 |
Pockets
18 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 807 | 0.75 | 0.79 | 70 | empty |
| 2 | 1057 | 0.73 | 0.76 | 88 | empty |
| 3 | 760 | 0.70 | 0.76 | 63 | empty |
| 4 | 585 | 0.69 | 0.78 | 57 | empty |
| 5 | 69 | 0.68 | 0.94 | 19 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A6QM06
- Elsewhere: UniProt A6QM06 · AlphaFold DB A6QM06
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