MolNFT v1 · #421070 · protein
AlphaFold monomer V2.0 prediction for sodium- and chloride-dependent glycine transporter 2 (A7Y2X0)
A7Y2X0: “AlphaFold monomer V2.0 prediction for sodium- and chloride-dependent glycine transporter 2 (A7Y2X0)”. 6 pockets (best druggability 0.80). MolNFT v1 #421070 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7Y2X0
- Type
- protein
- Length
- 790 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- Sodium- and chloride-dependent glycine transporter 2
- UniProt
- A7Y2X0
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 52% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium- and chloride-dependent glycine transporter 2 | protein | 790 | 52% helix, 3% strand | A7Y2X0 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 834 | 0.80 | 0.83 | 64 | empty |
| 2 | 212 | 0.56 | 0.79 | 21 | empty |
| 3 | 172 | 0.51 | 0.78 | 28 | empty |
| 4 | 86 | 0.39 | 0.78 | 22 | empty |
| 5 | 112 | 0.36 | 0.73 | 21 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7Y2X0
- Elsewhere: UniProt A7Y2X0 · AlphaFold DB A7Y2X0
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