MolNFT v1 · #421066 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (P31652)
P31652: “AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (P31652)”. 6 pockets (best druggability 0.79). MolNFT v1 #421066 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31652
- Type
- protein
- Length
- 630 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4B8122b57F10612F243dd42D8a8F4DbA5bC520cf
- Molecule
- Sodium-dependent serotonin transporter
- UniProt
- P31652
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 64% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent serotonin transporter | protein | 630 | 64% helix, 2% strand | P31652 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 789 | 0.79 | 0.82 | 77 | empty |
| 2 | 534 | 0.68 | 0.78 | 41 | empty |
| 3 | 87 | 0.52 | 0.83 | 16 | empty |
| 4 | 62 | 0.33 | 0.75 | 15 | empty |
| 5 | 67 | 0.29 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31652
- Elsewhere: UniProt P31652 · AlphaFold DB P31652
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