MolNFT v1 · #421065 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (Q60857)
Q60857: “AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (Q60857)”. 5 pockets (best druggability 0.79). MolNFT v1 #421065 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q60857
- Type
- protein
- Length
- 630 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x50c90613725017760519048B947c72787082125b
- Molecule
- Sodium-dependent serotonin transporter
- UniProt
- Q60857
- Pockets
- 5 · best druggability 0.79
Structure
1 distinct chain · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent serotonin transporter | protein | 630 | 63% helix, 2% strand | Q60857 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1041 | 0.79 | 0.80 | 94 | empty |
| 2 | 571 | 0.68 | 0.78 | 44 | empty |
| 3 | 90 | 0.51 | 0.82 | 15 | empty |
| 4 | 70 | 0.34 | 0.75 | 19 | empty |
| 5 | 60 | 0.33 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60857
- Elsewhere: UniProt Q60857 · AlphaFold DB Q60857
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