MolNFT v1 · #421061 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (O35899)
O35899: “AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (O35899)”. 5 pockets (best druggability 0.80). MolNFT v1 #421061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35899
- Type
- protein
- Length
- 630 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x133E079e1cB0870fc07292176c48cFF7F4BEb7C7
- Molecule
- Sodium-dependent serotonin transporter
- UniProt
- O35899
- Pockets
- 5 · best druggability 0.80
Structure
1 distinct chain · 64% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent serotonin transporter | protein | 630 | 64% helix, 2% strand | O35899 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 865 | 0.80 | 0.82 | 86 | empty |
| 2 | 365 | 0.64 | 0.79 | 28 | empty |
| 3 | 86 | 0.47 | 0.81 | 15 | empty |
| 4 | 118 | 0.40 | 0.75 | 18 | empty |
| 5 | 80 | 0.35 | 0.75 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35899
- Elsewhere: UniProt O35899 · AlphaFold DB O35899
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