MolNFT v1 · #421060 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (Q9XT49)
Q9XT49: “AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (Q9XT49)”. 3 pockets (best druggability 0.79). MolNFT v1 #421060 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9XT49
- Type
- protein
- Length
- 630 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xfEFC4162A0D2196abE0a0A681857dF0e98778b9C
- Molecule
- Sodium-dependent serotonin transporter
- UniProt
- Q9XT49
- Pockets
- 3 · best druggability 0.79
Structure
1 distinct chain · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent serotonin transporter | protein | 630 | 63% helix, 2% strand | Q9XT49 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 863 | 0.79 | 0.82 | 82 | empty |
| 2 | 333 | 0.52 | 0.74 | 33 | empty |
| 3 | 80 | 0.44 | 0.80 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XT49
- Elsewhere: UniProt Q9XT49 · AlphaFold DB Q9XT49
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