MolNFT v1 · #421054 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent noradrenaline transporter (O55192)
O55192: “AlphaFold monomer V2.0 prediction for sodium-dependent noradrenaline transporter (O55192)”. 5 pockets (best druggability 0.82). MolNFT v1 #421054 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O55192
- Type
- protein
- Length
- 617 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd466D587e3186d7527A9561e4d2cAc3eBff31f40
- Molecule
- Sodium-dependent noradrenaline transporter
- UniProt
- O55192
- Pockets
- 5 · best druggability 0.82
Structure
1 distinct chain · 68% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent noradrenaline transporter | protein | 617 | 68% helix, 1% strand | O55192 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 925 | 0.82 | 0.83 | 80 | empty |
| 2 | 106 | 0.43 | 0.78 | 19 | empty |
| 3 | 68 | 0.39 | 0.79 | 18 | empty |
| 4 | 83 | 0.33 | 0.73 | 14 | empty |
| 5 | 68 | 0.32 | 0.75 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O55192
- Elsewhere: UniProt O55192 · AlphaFold DB O55192
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