MolNFT v1 · #421052 · protein
AlphaFold monomer V2.0 prediction for sodium-dependent noradrenaline transporter (P51143)
P51143: “AlphaFold monomer V2.0 prediction for sodium-dependent noradrenaline transporter (P51143)”. 7 pockets (best druggability 0.81). MolNFT v1 #421052 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P51143
- Type
- protein
- Length
- 615 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- Sodium-dependent noradrenaline transporter
- UniProt
- P51143
- Pockets
- 7 · best druggability 0.81
Structure
1 distinct chain · 68% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium-dependent noradrenaline transporter | protein | 615 | 68% helix, 4% strand | P51143 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1014 | 0.81 | 0.82 | 82 | empty |
| 2 | 105 | 0.50 | 0.81 | 13 | empty |
| 3 | 227 | 0.45 | 0.73 | 33 | empty |
| 4 | 113 | 0.43 | 0.78 | 20 | empty |
| 5 | 81 | 0.37 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51143
- Elsewhere: UniProt P51143 · AlphaFold DB P51143
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