MolNFT v1 · #421050 · protein
AlphaFold monomer V2.0 prediction for sodium- and chloride-dependent GABA transporter 1 (P48057)
P48057: “AlphaFold monomer V2.0 prediction for sodium- and chloride-dependent GABA transporter 1 (P48057)”. 6 pockets (best druggability 0.77). MolNFT v1 #421050 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P48057
- Type
- protein
- Length
- 598 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2B6383898c41F2462737128e3CAF97Eebe0482a0
- Molecule
- Sodium- and chloride-dependent GABA transporter 1
- UniProt
- P48057
- Pockets
- 6 · best druggability 0.77
Structure
1 distinct chain · 67% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium- and chloride-dependent GABA transporter 1 | protein | 598 | 67% helix, 2% strand | P48057 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 778 | 0.77 | 0.81 | 69 | empty |
| 2 | 56 | 0.44 | 0.83 | 16 | empty |
| 3 | 134 | 0.44 | 0.77 | 19 | empty |
| 4 | 166 | 0.42 | 0.73 | 25 | empty |
| 5 | 94 | 0.36 | 0.75 | 20 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48057
- Elsewhere: UniProt P48057 · AlphaFold DB P48057
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