MolNFT v1 · #420987 · protein
AlphaFold monomer V2.0 prediction for SODIUM/MYO-inositol cotransporter 2 (Q28728)
Q28728: “AlphaFold monomer V2.0 prediction for SODIUM/MYO-inositol cotransporter 2 (Q28728)”. 6 pockets (best druggability 0.80). MolNFT v1 #420987 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q28728
- Type
- protein
- Length
- 674 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
- Molecule
- SODIUM/MYO-inositol cotransporter 2
- UniProt
- Q28728
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/MYO-inositol cotransporter 2 | protein | 674 | 66% helix, 1% strand | Q28728 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.80 | 0.97 | 31 | empty |
| 2 | 715 | 0.77 | 0.82 | 62 | empty |
| 3 | 155 | 0.51 | 0.79 | 37 | empty |
| 4 | 72 | 0.49 | 0.84 | 21 | empty |
| 5 | 88 | 0.41 | 0.78 | 16 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q28728
- Elsewhere: UniProt Q28728 · AlphaFold DB Q28728
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