MolNFT v1 · #420984 · protein
AlphaFold monomer V2.0 prediction for SODIUM/MYO-inositol cotransporter 2 (Q8WWX8)
Q8WWX8: “AlphaFold monomer V2.0 prediction for SODIUM/MYO-inositol cotransporter 2 (Q8WWX8)”. 7 pockets (best druggability 0.81). MolNFT v1 #420984 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8WWX8
- Type
- protein
- Length
- 675 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- SODIUM/MYO-inositol cotransporter 2
- UniProt
- Q8WWX8
- Pockets
- 7 · best druggability 0.81
Structure
1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/MYO-inositol cotransporter 2 | protein | 675 | 66% helix, 1% strand | Q8WWX8 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 154 | 0.81 | 0.97 | 31 | empty |
| 2 | 680 | 0.75 | 0.81 | 56 | empty |
| 3 | 62 | 0.60 | 0.91 | 21 | empty |
| 4 | 56 | 0.56 | 0.89 | 21 | empty |
| 5 | 89 | 0.45 | 0.79 | 17 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WWX8
- Elsewhere: UniProt Q8WWX8 · AlphaFold DB Q8WWX8
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