MolNFT v1 · #420571 · protein
AlphaFold monomer V2.0 prediction for saxiphilin (P31226)
P31226: “AlphaFold monomer V2.0 prediction for saxiphilin (P31226)”. 14 pockets (best druggability 0.78). MolNFT v1 #420571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31226
- Type
- protein
- Length
- 844 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Saxiphilin
- UniProt
- P31226
- Pockets
- 14 · best druggability 0.78
Structure
1 distinct chain · 30% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Saxiphilin | protein | 844 | 30% helix, 17% strand | P31226 |
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1071 | 0.78 | 0.79 | 75 | empty |
| 2 | 103 | 0.76 | 0.97 | 25 | empty |
| 3 | 678 | 0.70 | 0.77 | 64 | empty |
| 4 | 608 | 0.67 | 0.77 | 62 | empty |
| 5 | 194 | 0.51 | 0.77 | 26 | empty |
Modifications
Observed in the structure: 21 disulfide (disulfide).
Compared structures
- 8D6Q · Rana catesbeiana saxiphilin mutant - Y558I · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 8D6U · Rana catesbeiana saxiphilin:F-STX (soaked) · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 8D6T · Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal) · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 8D6S · Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal) · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 8D6P · Rana catesbeiana saxiphilin mutant - Y558A · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 6O0D · Saxiphilin Apo structure · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 6O0D · Saxiphilin apo structure · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 6O0F · Saxiphilin:STX complex, co-crystal · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6O0F · SAXIPHILIN:STX complex, co-crystal · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6O0E · Saxiphilin:STX complex, soaking · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6O0E · SAXIPHILIN:STX complex, soaking · an experimental structure of the same protein · chain A against B, TM-score 0.73
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31226
- Elsewhere: UniProt P31226 · AlphaFold DB P31226
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