MolNFT v1 · #420409 · protein

AlphaFold monomer V2.0 prediction for DNA-binding protein SATB1 (Q60611)

Q60611: “AlphaFold monomer V2.0 prediction for DNA-binding protein SATB1 (Q60611)”. 4 pockets (best druggability 0.68). MolNFT v1 #420409 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q60611
Type: protein
Length: 764 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7Ff705009366ACF09A4eD7a1FeA77EACe06d7FfF
Molecule: DNA-binding protein SATB1
UniProt: Q60611
Pockets: 4 · best druggability 0.68

Structure

1 distinct chain · 39% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-binding protein SATB1	protein	764	39% helix, 5% strand	Q60611

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	443	0.68	0.79	31	empty
2	398	0.65	0.79	44	empty
3	285	0.51	0.74	26	empty
4	58	0.26	0.73	16	empty

Compared structures

4Q2J · A novel structure-based mechanism for DNA-binding of SATB1 · an experimental structure of the same protein · chain A against A, TM-score 0.14
4Q2J · A novel structure-based mechanism for DNA-binding of SATB1 · an experimental structure of the same protein · chain A against A, TM-score 0.14

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q60611
Elsewhere: UniProt Q60611 · AlphaFold DB Q60611

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