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MolNFT v1 · #420408 · protein

AlphaFold monomer V2.0 prediction for DNA-binding protein SATB1 (Q01826)

Q01826: “AlphaFold monomer V2.0 prediction for DNA-binding protein SATB1 (Q01826)”. 7 pockets (best druggability 0.67). MolNFT v1 #420408 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q01826
Type
protein
Length
763 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
Molecule
DNA-binding protein SATB1
UniProt
Q01826
Pockets
7 · best druggability 0.67

Structure

1 distinct chain · 40% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-binding protein SATB1protein76340% helix, 6% strandQ01826

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14390.670.7936empty
22240.550.7829empty
31630.420.7423empty
41040.330.7219empty
5910.330.7321empty

Compared structures

  • 3TUO · Crystal structure of N-terminal domain of DNA-binding protein satb1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
  • 3TUO · Crystal structure of N-terminal domain of DNA-binding protein SATB1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
  • 1YSE · Solution structure of the mar-binding domain of SATB1 · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 1YSE · Solution structure of the MAR-binding domain of SATB1 · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 2O4A · Crystal Structure of the N-terminal CUT Domain of SATB1 Bound to Matrix Attachment Region… · an experimental structure of the same protein · chain A against A, TM-score 0.11
  • 2O4A · Crystal structure of the N-terminal cut domain of SATB1 bound to matrix attachment region… · an experimental structure of the same protein · chain A against A, TM-score 0.11

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