GL1X · GenesisL1 explorer

MolNFT v1 · #420354 · protein

AlphaFold monomer V2.0 prediction for SAM and SH3 domain-containing protein 3 (Q8K352)

Q8K352: “AlphaFold monomer V2.0 prediction for SAM and SH3 domain-containing protein 3 (Q8K352)”. 1 pocket (best druggability 0.40). MolNFT v1 #420354 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8K352
Type
protein
Length
380 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x429aA010A80A47FF4a2777bB34A2bba144d19df2
Molecule
SAM and SH3 domain-containing protein 3
UniProt
Q8K352
Pockets
1 · best druggability 0.40

Structure

1 distinct chain · 16% helix, 8% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASAM and SH3 domain-containing protein 3protein38016% helix, 8% strandQ8K352

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11210.400.7520empty

Compared structures

  • 6G8O · Solution structure of the cross-linked SAM domain dimer of murine SLY1 · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 6FXF · Crystal structure of the SAM domain of murine SLY1 · an experimental structure of the same protein · chain A against A, TM-score 0.17

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