MolNFT v1 · #420314 · protein

AlphaFold monomer V2.0 prediction for spindle assembly abnormal protein 6 homolog (Q6UVJ0)

Q6UVJ0: “AlphaFold monomer V2.0 prediction for spindle assembly abnormal protein 6 homolog (Q6UVJ0)”. 1 pocket (best druggability 0.29). MolNFT v1 #420314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6UVJ0
Type: protein
Length: 657 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule: Spindle assembly abnormal protein 6 homolog
UniProt: Q6UVJ0
Pockets: 1 · best druggability 0.29

Structure

1 distinct chain · 55% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Spindle assembly abnormal protein 6 homolog	protein	657	55% helix, 10% strand	Q6UVJ0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.29	0.74	11	empty

Compared structures

6Z4A · Structure of the human sas-6 N-terminal domain, F131E mutant · an experimental structure of the same protein · chain A against A, TM-score 0.22
6Z4A · Structure of the human SAS-6 N-terminal domain, F131E mutant · an experimental structure of the same protein · chain A against A, TM-score 0.22
6YS4 · Structure of the Homo sapiens SAS-6 coiled-coil domain · an experimental structure of the same protein · chain A against E, TM-score 0.15
6YS4 · Structure of the homo sapiens sas-6 coiled-coil domain · an experimental structure of the same protein · chain A against B, TM-score 0.15

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6UVJ0
Elsewhere: UniProt Q6UVJ0 · AlphaFold DB Q6UVJ0

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