MolNFT v1 · #420204 · protein

AlphaFold monomer V2.0 prediction for NAD(+) hydrolase SARM1 (I3L5V6)

I3L5V6: “AlphaFold monomer V2.0 prediction for NAD(+) hydrolase SARM1 (I3L5V6)”. 6 pockets (best druggability 0.72). MolNFT v1 #420204 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: I3L5V6
Type: protein
Length: 725 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
Molecule: NAD(+) hydrolase SARM1
UniProt: I3L5V6
Pockets: 6 · best druggability 0.72

Structure

1 distinct chain · 60% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NAD(+) hydrolase SARM1	protein	725	60% helix, 3% strand	I3L5V6

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	518	0.72	0.81	54	empty
2	206	0.54	0.78	21	empty
3	198	0.48	0.75	21	empty
4	109	0.44	0.78	19	empty
5	122	0.41	0.75	22	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt I3L5V6
Elsewhere: UniProt I3L5V6 · AlphaFold DB I3L5V6

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